通用名称：阿那格雷

英文名称：Anagrelide

中文别名：氯喹咪唑酮、盐酸阿那格利

英文别名：Agrylin、Anagrelide Hydrochloride

【适应症】

1.Anagrelide lowers the number of blood clotting cells (called platelets) in the body. This helps to prevent blood clots from forming.

2.Anagrelide is used to treat essential thrombocytosis (too many blood clotting cells in the body).

3.Anagrelide may also be used for purposes other than those listed in this medication guide.

【用法用量】

1.Take anagrelide exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

2.Take each dose with a full glass of water.

3.Your doctor will need to monitor your blood with blood tests before starting treatment with anagrelide, every 2 days for the first week of treatment, and at least weekly thereafter until the desired maintenance dosage is reached.

4.Store anagrelide at room temperature away from moisture and heat.

【注意事项】

1.Your doctor will need to monitor your blood with blood tests before starting treatment with anagrelide, every 2 days for the first week of treatment, and at least weekly thereafter until the desired maintenance dosage is reached.

2.Tell your doctor and dentist that you are taking this medication before undergoing any surgical procedures.

If Miss a Dose: 1.Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Contraindications: 1.Before taking anagrelide, tell your doctor if you have

* heart disease,

*kidney disease, or

*liver disease.

2.You may not be able to take anagrelide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

3.Anagrelide is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

4.It is not known whether anagrelide passes into breast milk. Do not take this medication without first talking to your doctor if you are breast feeding a baby.

5.Anagrelide is not approved for use by children younger than 16 years old.

Special Concerns: 1.Tell your doctor and dentist that you are taking this medication before undergoing any surgical procedures.

【不良反应】

1.If you experience any of the following serious side effects, stop taking anagrelide and seek emergency medical attention or notify your doctor immediately:

*an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

*fast, slow, or irregular heartbeat;

*chest pain;

*swelling of the hands, feet, or legs;

*shortness of breath or difficulty in breathing;

*seizures;

*bloody or black vomit or stools;

*abdominal pain;

*unusual, prolonged, or severe bleeding or bruising; or

*a bleeding nose.

2.Other, less serious side effects may also occur. Continue to take anagrelide and talk to your doctor if you experience

*headache;

*diarrhea;

*tingling or numbness in the hands or feet;

*upset stomach, nausea, or vomiting;

*dizziness;

*gas;

*fever;

*a rash or itching;

*loss of appetite;

*sore throat;

*cough; or

*back pain.

3.Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

【相互作用】

1.There are no known interactions between anagrelide and other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

【药物过量】

1.Seek emergency medical attention.

2.Symptoms of a anagrelide overdose are unknown but might include bleeding and blood in the vomit or stool.