词条 | 蒋星红 |
释义 | 蒋星红,女,博士,教授,博士生导师。苏州大学医学部基础医学与生物科学学院神经生物学教研室(研究室)主任,苏州大学医学部副主任,江苏省生理科学学会副理长,中国生理学会理事,江苏省高等学校医药教育研究会常务理事。 简介二十多年来一直从事生理学、神经生物学的教学工作和神经生物学的基础研究。曾先后在意大利catania大学和日本昭和大学作访问学者,获医学博士学位。 详细科研项目早期的研究工作主要是痛觉的调制,参与了三项国家自然科学基金的课题研究。自日本留学归国后,主要研究方向是神经内分泌免疫调制和神经干细胞生物学。已发表论文50余篇,参编教材或论著十部,获省部级科技进步三等奖四项。主持中日校际合作研究课题“神经干细胞的定向分化”和“神经系统与免疫系统相互影响”。同时,还与美国佛罗里达州立大学医学院虞献民教授合作,开展慢性痛的中枢机制研究;与秦正红教授合作,进行蛇毒的镇痛作用研究。是苏州大学衰老与神经疾病实验室,神经可塑性和功能调节研究方向学科带头人。 发表论文1. J-C Wu, Z-Q Liang, Z-H Qin. (2006) Quality Control System of the Endoplasmic Reticulum and Related Diseases. Acta Biochem Biophys Sin 38:219-226. 2. Y Wang, Z-L Gu, Y Cao, Z-Q Liang, R Han, M C Bennett, Z-H Qin. (2006) Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum. Brain Res 1071:245-249. 3. H-L Zhang, R Han, Z-X Chen, B-W Chen, Z-L Gu, P F Reid, L N Raymond, Z-H Qin. (2006) Opiate and Acetylcholine-independent Analgesic Actions of Crotoxin. Toxicon 16:1-7. 4. Z-X Chen, H-L Zhang, Z-L Gu, B-W Chen, R Han, P F Reid, L N Raymond, Z-H Qin. (2006) A long form a-neurotoxin from cobra venom produces potent opioid-independent analgesia. Acta Pharmacol Sin 5:402-408. 5. C-H Yan, Z-Q Liang, Z-L Gu, Y-P Yang, P F Reid, Z-H Qin. (2006) Contributions of autophagic and apoptotic mechanisms to crotoxin-induced death of K562 cells. Toxicon 47:521-530. 6. Y Zhu, Z-L Gu, Z-Q Liang, H-L Zhang, Z-H Qin. (2006) Prostaglandin A1 inhibits the rise in intracellular calcium concentration,TXA2 production and platelet activation. Acta Pharmacol Sin 27:549-554. 7. X-H Xu, H-L Zhang, R Han, Z-L Gu, Z-H Qin. (2006) Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia. Brain Res 110:154-162. 8. L-H Wang, Z-H Qin. (2006) Animal models of Huntington’s disease: their implications in uncovering pathogenic mechanisms and developing therapies. Acta Pharmacol Sin 27:1277-1388. 9. L-Y Tao, X-P Chen, Z-H Qin. (2006) Could NF-kB and caspase-3 be markers for estimation of post-interval of human traumatic brain injury? Forensic Sci Int 162:174–177. 10. Q-B Zhang, X-Y Ji, Q Huang, et al. (2006) Differentiation profile of brain tumor stm cells: a comparative study with neuronal stem cells. Cell Research 16:1-7. 11. F Lin, Z-L Gu, Z-H Qin. (2005) The Role of autophagy in cell metabolism and disease. Progress Biochem Biophys 32:298-203. 12. Z-H Qin, J Wang, Z-L Gu. (2005) Development of novel therapies for huntington’s disease: hope and challenge. Acta Pharmacol Sin 26:129-142. 13. L-Y Tao, X-P Chen, Z-H Qin. (2005) A Fatal chronic Ketamine Poisoning. J Forensic Sci 50:173-176. 14. Y-P Yang, Z-Q Liang, Z-L Gu, Z-H Qin. (2005) Molecular mechanism and regulation of autophagy. Acta Pharmacol Sin 12:1421-1434. 15. C Yi, Z-L Gu, F Lin, R Han, Z-H Qin. (2005) Caspase-1 inhibitor Ac-YVAD-CHO attuneates quinolinic acid-induced increases in p53 and apoptosis in rat striatum. Acta Pharmacol Sin 26:150-154. 16. H-L Zhang, Z-H Huang, Z-L Gu, Y Zhu, Z-Q Liang, R Han, X-X Wang, T N Chase, Z-H Qin. (2005) Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia. Brain Res 1039: 203-206. 17. D Cai, J M Mataraza, Z-H Qin, Z Huang, J Huang,T C Chiles, D Carnahan1, K Kempa, Z Ren. (2005) Highly Efficient Molecular Delivery into Mammalian Cells Using Carbon Nanotube Spearing. Nat Methods 2:449-454. 18. Z-Q Liang, X-X Wang, Y Wang, D-M Chuang, M DiFiglia, T N Chase, Z-H Qin. (2005) Susceptibility of Striatal Neurons to Excitotoxic Injury Correlates with Basal Levels of Bcl-2 and the Induction of P53 and c-Myc Immunoreactivity. Neurobiol Disease 20:562-573. 19. S Xu, S-Y Guo, X-H Jiang, T Umezawa, T Hisamitsu. (2005) The role of noepinephrine and nitric oxide in activities of rat arginine vasopressin neurons in response to immune challerge. Neuroscience Letters 383:231-235. 20. Q Zhu, S-Y Guo, S Gong, Q-Z Yin, T Hisamitsu, X-H Jiang. (2005) Losartan blocks the excitaelectrophysiological and immunocytochemical evidence in PVN: tory effect of peripheral hypertonic stimulation on vasopressinergic neurons. Neuroscience Letters 380(1-2):12-6. 21. X-H Jiang, S-Y Guo, S Xu, Q-Z Yin, T Hisamitsu. (2004) Sympathetic Nervous System Mediates Cold Stress-Induced Suppression of Natural Killer Cytotoxicity. Neuroscience Letters 357:1-4. 22. Z-H Qin and Z-L Gu. (2004) Huntingtin processing in pathogenesis of Huntington disease. Acta Pharmacol Sin 25:1243-1249. 23.W. Y. Chan, C-L Xia, D-C Dong, C. W. Heizmann and D. T. Yew. (2003) Differential Expression of S100 Proteins in the Developing Human Hippocampus and Temporal Cortex. Microscopy Res Tech 60:600–613. 24.C-L Xia, Z-W Du, Z-Y Liu, Q Huang, W. Y. Chan. (2003) A2B5 lineages of human astrocytic tumors and their recurrence. Int J Oncol 23(2): 353–361. 25. S Xu, S-Y Guo, X-H Jiang, Q-Z Yin, T Umezawa, T Hisamitsu. (2003) Effect of indomethacin on the c –fos expression in AVP and TH neurons in rat brain induced by lipopolysaccharide. Brain Research 966(1):13-18. |
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