人物简介

研究领域

科研项目

代表性论文

人物简介

霍聪德，1978年9月出生，西北师范大学化学化工学院教授

博士后经历：

2007.5.-2009.6.: 加拿大麦吉尔大学 (McGill University)

2005.7.-2007.4.: 香港理工大学 (the Hong Kong Polytechnic University)

高等教育经历：

2000.9.-2005.6.: 兰州大学，有机化学专业博士

1996.9.-2000.6.: 兰州大学，化学专业学士

研究领域

有机反应方法学；绿色有机化学；药物合成化学

科研项目

国家自然科学基金青年基金；教育部科学技术研究重点项目；教育部博士点基金新教师类课题；教育部留学回国人员科研启动基金；甘肃省留学人员科技活动项目择优资助；西北师范大学自然科学类青年教师科研基金项目

代表性论文

1，Huo, C.; Chan, T. H., A novel liquid-phase strategy for organic synthesis using organic ions as soluble supports, Chemical Society Reviews 2010, 39, 2977-3006. (IF 26.583)

2，Huo, C.; Chan, T. H., Carbon tetrabromide/sodium triphenylphosphine-m-sulfonate (TPPMS) as an efficient and easily recoverable catalyst for acetalization and tetrahydropyranylation reactions, Advanced Synthesis & Catalysis 2009, 351, 1933-1938. (IF 5.250)

3，Huo, C.; He, X.; Chan, T. H., Zwitterionic Phosphonium Sulfonates as Easily Phase-Separable Ion-Tagged Wittig Reagents, Journal of Organic Chemistry 2008, 73, 8583-8586. (IF 4.002)

4，Huo, C.; Yang, H.; Cui, Q. C.; Dou, Q. P.; Chan, T. H., Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs, Bioorganic & Medicinal Chemistry 2010, 18, 1252-1258. (IF 2.978)

5，Huo, C.; Shi, G.; Lam, W. H.; Chen, D.; Cui, Q. C.; Dou, Q. P.; Chan, T. H., Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract, Canadian Journal of Chemistry 2008, 86, 495-502. (IF 1.374)

6，Huo, C.; Wei, R.; Zhang, W.; Yang, L.; Liu, Z.-L., Cation Radical [3+2] Cycloaddition of Chalcone Epoxides (II): A Facile Synthesis of Highly-Substituted 1, 3-Oxazolidines, Synlett 2005, 161-163. (IF 2.447)

7, Huo, C.; Jia, X.; Zhang, W.; Yang, L.; Liu, Z.-L., Cation Radical [3 + 2] Cycloaddition of Chalcone Epoxides: A Facile Synthesis of Highly Substituted Tetrahydrofurans, Synlett 2004, 251-254. (IF 2.447)

8, Huo, C.; Wan, S. B.; Lam, W. H.; Li, L., Wang Z.; Dou, Q. P.; Chan, T. H., The Challenge of Developing Green Tea Polyphenols as Therapeutic Agents, Inflammopharmacology 2008, 16, 248-252.

9，Landis, K. R.; Huo, C.; Chen, D.; Milacic, V.; Shi, G.; Chan, T. H.; Dou, Q. P., A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate as a potential anticancer agent, Cancer Research 2007, 67, 4303-4310. (IF 8.234)

10, Chan, T. H.; Huo, C.; He, X., Zwitterionic Phosphonium Salts, Patent, WO 2010/012096.