男，1962年出生，山东平邑人。 任山东大学教授,实验诊断学博士研究生导师。山东省医科院免疫学硕士研究生导师。

简介

发表的论文

简介

汪运山 医生

地址：山东省济南市解放路105号

邮编：250013

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山东大学附属济南市中心医院医学实验诊断中心主任，主任医师(II级)

山东大学教授，实验诊断学博士研究生导师

山东省医学科学院免疫学兼职研究员，免疫学硕士研究生导师

山东省移植与组织工程技术研究中心主任

省市共建肿瘤防治靶向分子研究重点实验室主任

济南迪恩法医司法鉴定所负责人，法医师

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山东医药杂志编委

检验医学与临床杂志副主编

中华肿瘤防治杂志编委

山东大学学报（医学版）编委

主要从事肿瘤微环境分子信号通路的研究

负责细胞与干细胞转化应用方面的研究

负责血缘关系鉴定和个体识别报告的签发

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先后承担或参与了国家“973”子项目、国家自然科学基金、卫生部“十一五”专项基金等10项课题。自2003年发表第一篇被SCI收录论文后，迄今发表被SCI收录论文近30余篇。

发表的论文

2003．07—2012．02发表被SCI收录论文（* 通讯作者）

1. Zhang Y, Lu N, Xue Y, Zhang M, Li Y, Si Y, Bian X, Jia Y, Wang Y*..Expression of immunoglobulin-like transcript (ILT)2 and ILT3 in human gastric cancer and its clinical significance.Mol Med Report. 2012 Jan 9. doi: 10.3892/mmr.2012.744. [Epub ahead of print]

2. Gai Z, Liang M, Zhang Y, Zhang S, Jin C, Wang SW, Sun L, Zhou N, Zhang Q, Sun Y, Ding SJ, Li C, Gu W, Zhang F, Wang Y, Bian P, Li X, Wang Z, Song X, Wang X, Xu A, Bi Z, Chen S, Li D. Person-to-Person Transmission of Severe Fever With Thrombocytopenia Syndrome Bunyavirus Through Blood Contact. Clin Infect Dis. 2012 Jan;54(2):249-52

3. Zheng Y, Shi X, Wang M, Jia Y, Li B, Zhang Y, Liu Q, Wang Y*.The increased expression of DEC1 gene is related to HIF-1α protein in gastric cancer cell lines.Mol Biol Rep. 2011 Jul 21. [Epub ahead of print]

4. Zhao X, Yang W, Shi C, Ma W, Liu J, Wang Y*, Jiang G. The G1 phase arrest and apoptosis by intrinsic pathway induced by valproic acid inhibit proliferation of BGC-823 gastric carcinoma cells. Tumour Biol. 2011;32(2):335-46.

5. Shi XH, Zheng Y, Sun Q, Cui J, Liu QH, Qü F, Wang YS*. DEC1 nuclear expression: A marker of differentiation grade in hepatocellular carcinoma. World J Gastroenterol. 2011;17(15):2037-43.

6. Zhao J, Wang Y, Wang H, Jiang C, Liu Z, Meng X, Song G, Cheng N, Graviss EA, Ma X. Low agreement between the T-SPOT®.TB assay and the tuberculin skin test among college students in China. Int J Tuberc Lung Dis. 2011;15(1):134-6

7. Xiaohong Shi, Yan Zheng, Wanshan Ma, Yunshan Wang*. Possible involvement of DEC1 on the adverse effects of quinolone antibiotics. Toxicology，2010; 271(1-2):1-4.

8. Zhang MX, Zhao X, Wang ZG, Zhao WM, Wang YS*. Constitutive activation of signal transducer and activator of transcription 3 regulates expression of vascular endothelial growth factor in human meningioma differentiation. J Cancer Res Clin Oncol. 2010, 136(7):981-8.

9. L.P. Sun, X.L. Ma, H.X. Liu, Y.S. Wang* and X.F. Li. No association of polymorphisms in the suppressor of cytokine signaling (SOCS)-3 with rheumatoid arthritis in the Chinese Han population. Genetics and Molecular Research, 2010, 9 (3): 1518-1524.

10. Y ZHANG, Y LIU, N LU, NN SHAN, GX ZHENG, SM ZHAO, X ZOU, YJ GAO, YJ LI1 AND YS WANG*. Expression of the Genes Encoding Human Leucocyte Antigens-A, -B, -DP, -DQ and -G in Gastric Cancer Patients. The Journal of International Medical Research, 2010; 38(3):949-56.

11. Zheng Y, Jia Y, Wang Y*, Wang M, Li B, Shi X, Ma X, Xiao D, Sun Y. The hypoxia-regulated transcription factor DEC1 (Stra13,SHARP-2) and its expression in gastric cancer. Omics : a journal of integrative biology, 2009;13(4):301-306.

12. Sun Y, Liu J, Gao P, Wang Y, Liu C. Expression of Ig-like transcript 4 inhibitory receptor in human non-small cell lung cancer. Chest. 2008, 134(4):783-788.

13. Wang P, Liu Z, Wu C, Zhu B, Wang Y, Xu H. Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium. Transplant Proc. 2008 40(8):2729-2733.

14. Zhu L, Fang Y, Liu Z, Wang P, Wang Y, Xu H. Rabbit anti-human leukocyte polyclonal antibody inhibits xenogeneic cell-mediated immune responses. Transplant Proc. 2008; 40(8):2760-2763.

15. GAO Na, LI Zhi-hong, DING Bu-tong, CHEN Yun, WANG Yun-shan, QIAO Ying, GUO Nong-jian. Expression of ETV6 rearrangement in a subject with acute myeloid leukemia-M4Eo. Chinese Medical Journal. 2008; 121(17) :1744-1746.

16. Fang Y, Liu Z, Zhu L, Wang P, Wang Y, Xu H. CD4+ T-cell and monocyte interdependence during discordant xenoimmune responses. Transplant Proc. 2008; 40(8):2764-8.

17. Yong Zhang, Yinhua Wang, Yunshan Wang, Caisan Cui, Ping Huang, Xianliang Li, Shuang Liu, Corinne Lendon, Nongjian Guo. Platelet glycoprotein polymorphisms: Risk, in vivo expression and severity of atherothrombotic stroke in Chinese. Clinica Chimica Acta, 2007, 378:99–104

18. Yuping Sun, Yunshan Wang, Jianqiang Zhao, Ming Gu, Ricardo Giscombe, Ann Kari Lefvert, Xiongbiao Wang. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung cancer, 2006, 53:143-151

19. Haiji Sun, Yunshan Wang*, Xiaoli Ma, Fengyan Pei, Hongsheng Sun, Yuanchao Zhang, Bing Yu. A method of oligochip for SNP genotyping in the promoter region of the IL-1_ gene and its clinical application. Oligonucleotides. 2007, 17(3):336-342.

20. Yanfei Jia, Xiaoli Ma, Fang Zhou, Dongjie Xiao, Yunshan Wang*. Apoptosis of gastric cancer cell FU-97 induced by arsenic trioxide in vitro. Cell Research. 2006, 16(s):96-97.

21. An-La Hu, Xiao-Li Ma, Yan-fei Jia, Fang Zhou, Yun-Shan Wang*. Inhibition Effects of RNAi on alpha-fetoprotein Expression in human FU97 gastric carcinoma cell line. Cell Research; 2006; 16：S96.

22. Hongwei Qin, Anla Hu, Dongjie Xiao, Xiaoli Ma, Yunshan Wang*. Culture of endothelial progenitor cells from human peripheral blood and real-time identification by flow cytometry. Cell Research, 2006; 16:47-48.

23. Xiao-Li Ma, Hai-Ji Sun, Yun-Shan Wang, Shu-Hong Huang, Jing-Wu Xie, Hong-Wei Zhang. Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma. World J Gastroenterol. 2006, 12(25): 3965-3969.

24. Fang Zhou, Xiaoli Ma, Yanfei Jia, Dongjie Xiao, Yunshan Wang. Apoptosis of human gastric cancer cell line AGS induced by arsenic trioxide, cell research, 2006, 16(s):96-97.

25. Guosheng Jiang, Kehong Bi, Tianhua Tang, Junwei Wang, Yukun Zhang, Wei Zhang, Haiquan Ren, Houqiao Bai and Yunshan Wang*. Down-regulation of TRRAP-dependent hTERT and TRRAP-independent CAD activation by Myc/Max contributes to the differentiation of HL60 cells after exposure to DMSO. International Immunopharmacology, 2006, 6(7):1204-1213.

26. Tang-Hong Jia , Yun-Shan Wang* , Xiao-Li Ma , Hong Shen , Yong-Xin Hua , Yi-Lin Cao. Induction of Chondrocytes Differentiation from Rat Bone Marrow Stromal Cells and Gene Expression of Immune Proteins. Cell Research, 2006；16:S64.

27. Yunshan Wang*, Xiaoli Ma, Shanhui Sun，Bing Yu. Development of an oligochip for genotyping human leukocyte antigens-B51and its clinical application. Genetic Testing. 2005; 9(4):292-296.

28. Yun-Shan WANG*, Xiao-Li Ma, Tong-Gang Qi, Xiang-Dong Liu, Yue-Sheng Meng, Guang-Ju Guan. Downregulation of alpha-fetoprotein siRNA inhibits proliferation of SMMC-7721 cells. World J Gastroenterol. 2005; 11(38):6053-6055.

29. Yunshan Wang*, Shanhui Sun, Hong Shen, Lihua Jiang, Maoxiu Zhang, Dongjie Xiao, Yang Liu, Xiaoli Ma,Yong Zhang, Nongjian Guo,Tanghong Jia. Cross-reaction of SARS-CoV Antigen with Autoantibody in Autoimmune Diseases. Cell Mol Immunol. 2004; 1(4):304-307.

30. Wang YS*, Shen H, Sun SH, et al.Analysis of false-positive associated with antibody tests for SARS-CoV in autoinnnune disease patients.Applied Immunohistochemistry & Molecular Morphology. 2003；11(4):298-305，

在中华系列杂志和Pubmed收录期刊发表的中英文论文

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2． 济南汉族群体5个Y-SNP位点的多态性分析，法医学杂志，2011，03期

3． 美加明对人肺腺癌A549细胞增殖和迁移的影响，肿瘤， 2011，01期

4． 腺病毒介导RNAi抑制胃癌FU97细胞AFP基因表达的研究，中华肿瘤防治杂志， 2010，07期

5． 新一代多克隆抗体抑制异种细胞免疫反应的研究，中华器官移植杂志， 2009，02期

6． 胃癌组织转录调节因子DEC1表达及其临床意义的研究，中华肿瘤防治杂志 ，2009，13期

7． 重组人生长激素对烧伤大鼠肠源性脓毒症及其预后的影响，中华医院感染学杂志， 2009，06期

8． 丙戊酸钠调节组蛋白乙酰化对肝癌细胞浸润转移影响的研究，中华肿瘤防治杂志， 2009，02期

9． AFP、VEGF及STAT3在胃癌组织中的表达及意义，中华肿瘤防治杂志， 2008，10期

10． IL-1β血清水平及IL-1B和IL-1受体拮抗剂基因多态...， 中华微生物学和免疫学杂志， 2008，05期

11． 三氧化二砷对人AFP阳性胃癌细胞株FU97的作用及其...， 中华肿瘤防治杂志 ，2008，03期

12． RATG对CD4+细胞和CD8+细胞共刺激分子基因表达和...， 中华器官移植杂志 ，2008，09期

13． Identifiler~TM系统在单亲血缘关系鉴定中的突变观察与分析，法医学杂志，2008，03期

14． 人单核细胞共刺激分子在异种免疫反应中的表达及其作...， 中华器官移植杂志， 2008，10期

15． 胃癌组织中Sonic Hedgehog和VEGF表达及临床意义的...， 中华肿瘤防治杂志， 2007，24期

16． 骨髓增生异常综合征患者ETV6基因重排分析及其临床...， 中华血液学杂志， 2007，12期

17． 细胞因子基因多态性与胃腺癌关系的探讨，中华医学杂志， 2007，15期

18． 应用基因表达谱芯片研究人胃癌细胞周期和细胞凋亡相...， 中华肿瘤防治杂志， 2007，08期

19． IL-1B-31及-511基因多态性与结核易感性的相关性研究，中华微生物学和免疫学杂志， 2006，08期

20． 白塞病人白细胞抗原B51基因分型芯片的研制，中华检验医学杂志， 2005，09期

21． 人类白细胞抗原-B51与Behcet病葡萄膜炎的相关性研究，中华眼底病杂志， 2004，04期

22． 自身免疫病患者血清中传染性非典型肺炎冠状病毒抗体...， 中华检验医学杂志， 2004，05期

23． 系统性红斑狼疮患者辅助T细胞和细胞毒T细胞亚群的...， 中华检验医学杂志， 2004，06期

24． SLE患者血清中SARS-CoV抗体阳性原因分析，实验生物学报， 2003，04期

25． 胃癌组织及转移淋巴结中DC和NK细胞与VEGF表达及...， 中华微生物学和免疫学杂志， 2003，09期

26． 支气管哮喘患者血清巨噬细胞炎症蛋白1α的变化，中华结核和呼吸杂志， 2001，12期

27． 晚期卵巢癌患者联合化疗后癌细胞中DNA抗体的变化，中华妇产科杂志，1995，12期

28． 血小板提取液放置时间对血小板相关抗体测定结果的影响，中华医学检验杂志，1994，04期

29． RESTRICTION FRAGMENT LENGTH POLYMORPHISMS ASSOCIATED WITH FACTOR Ⅷ CARRIER DETECTION USING DNA RFLPs IN CHINESE，Journal of Shanghai Second Medical University ，1992年， 02

30． 应用PCR直接分析21-羟化酶基因B，中华医学遗传学杂志，1992，05期

另外，在其它期刊以第一作者或通讯作者，或参与发表的中文论文，分别见：

1． 中文科技期刊数据库

2．万方数据库