个人简历

1945年6月生

1970年毕业于中国科学技术大学

1978年至今，中国科学技术大学化学系任教，现为教授、博士生导师

期间：

1983-1985年，美国斯坦福大学访问学者，从事不对称合成研究

1985-1986年，美国华盛顿州立大学博士后，大环内酯新药的合成研究

1996.11-1998.2，美国佛罗里达州立大学访问教授，抗菌和抗癌新药合成研究

2001.9-2002.2，美国加州太平洋医学中心研究所，抗癌新药合成研究

主要研究方向

1 不对称合成，2 新药合成研究

目前在研的课题有:

1．野菊花中抗炎活性成分的分离、鉴别、结构修饰和活性评价（973前期，20万）

2．不对称频哪醇偶联反应研究（国家自然科学基金项目，23万）

获奖及荣誉

文章及专著

1. Li, D.-L.; Bao, H.-L.; Tan, Q.-T.; Cai, D.-M.; You, T.-P. Synthesis of Ribavirin Analogues Containing Amino Acids Residues, Synth. Commun. 2005, 35，1017..

2. Li, M-J; Jiang, C.; Li, M-Z. You. T-P., OSAR studies of 20(S)-camptothecin analogues as antitumor agents, J. Mol. Struc.: THEOCHEM, 2005, 723, 165.

3. Cai, D.-M; Lin, K.-H.; Li, M.-Z.; Wen, J.-W.; Li, H.-Y.; You, T.-P. Synthesis of Novel 1,3-Dioxolane Nucleoside Analogues, Chin. J. Chem. 2004, 22, 1425.

4. Li, Y.-G.; You, T.-P.* et al, Asymmetric pinacol coupling of aromatic aldehydes catalyzed by a new titanium-Schiff base complex, Tetrahedron:Asymmetry, 2004, 15, 1707.

5. Tian, Q.-S.; You, T.-P.* et al, Experimental and theoretical investigation of the relationship between the stericstructure of Schiff bases and the diastereoselectivity of pinacol produced from benzaldehyde, J. Mol. Cat. A: Chem. 2004, 219, 315.

6. Cai, D.-M.; You, T.-P.* et al, Ring-Expanded C-Nucleoside Analogues of Tiazofurin, Syn. Commun. 2004, 34, 159.

7. Tan, Q.-T.; You, T.-P.* et al, A Convenient Preparation of Enantiopure endo-2- Hydroxyepicamphor and endo-3-Hydroxyepicamphor From Camphoric Acid, Syn. Commun. 2004, 34, 2945.

8. Li, Y.-G.; You, T.-P.* et al, Enantioselective Pinacol Coupling of Aromatic Aldehydes Mediated by TiCl4(THF)2/Zn with Tartaric Ester, Chin. J. Chem. 2004, 22, 950.

9. Cai, D.-M.; You, T.-P.* et al, Synthesis of C-Nucleoside Analogues: 2-[2-(Hydronxymethyl)-1,3-dioxolan-5-yl]1,3-thiazole-4-carboxamide and 2-[2-(Mercapto methyl)-1,3-dioxolan-5-yl]1,3-thiazole-4-carboxamide, Chin. Chem. Lett. 2004, 15, 163.

10. Jiang, C., You, T.-P.* et al, QSAR Study of Catalytic Asymmetric Reaction with Topological Indices, J. Chem. Inf. Comput. Sci. 2003, 43, 1876

11. Tan, Q.-T.; You, T.-P.* et al, A Novel and Efficient Synthesis of Camphorquinone from Camphoric Acid, Synthesis, 2003, 12, 1869.

12. Li, Y.-G.; You, T.-P.* et al, Asymmetric Pinacol Coupling of Aromatic Aldehydes Catalyzed by TiCl4(THF)2-Zn/Chiral Diamines, Chin. J. Chem. 2003, 21, 1369.

13. Jiang, C.-S., You, T.-P.* et al, Asymmetric Cyclopropanation Catalyzed by Copper- (Schiff-Base) Complex with Double Chiral Centers, Chem. Res. Chin. U. 2003, 19(2), 238

14. Jiang, C.-S.; You, T.-P. et al, Asymmetric Cyclopropanation Catalyzed by a Series of Copper-(Schiff-Base) Complexes with Two Chiral Centers, Enantiomer, 2002, 7, 287.