| 词条 | 楼慧强 |
| 释义 | 教师简介楼慧强，男，教授，博士生导师。 2009年中国农业大学特聘教授，同年入选教育部“新世纪优秀人才和创新团队”。 主要以真核微生物酿酒酵母（ Saccharomyces cerevisiae ）为模式系统，在基因和蛋白相互作用网络水平探求基因组不稳定性的分子机理，及其与疾病/癌症发生的关系。目前致力于相互作用组学技术构建DNA复制期（即S期）的蛋白质调控网络。代表性论文包括Mol Cell封面文章等。 学习与工作经历2009.3- Professor, Department of Microbiology and Immunology, College of Biological Sciences, China Agricultural University. 2006.8-2009.3 CIRM Senior Research Fellow, Divisions of Chemistry and Biology, California Institute of Technology, USA. 2004.8-2006.8 Postdoctoral Scholar, Division of Chemistry and Chemical Engineering, California Institute of Technology, USA. 1997.9-2004.2 Doctor of Philosophy, Institute of Microbiology, Chinese Academy of Sciences, China. 1992.9-1997.7 Bachelor of Science, Department of Cell Biology and Genetics, Peking University, China. 研究方向In budding yeast: Genome instability, Diseases and Cancer. DNA replication and the S phase checkpoint. DNA damage and replication stress signaling pathways. Asymmetric segregation and cell aging. In herperthermophilic archaea: Genome stability under boiling growth temperature. Epigenetic adaptation to the extremely harsh environment 主讲课程研究生课程 《Progress in Microbiology》 《Advanced Progress in Microbiology》 《文献研读》 发表文章Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C. Reis, Martin Budd, Katsuhiko Shirahige, and Judith L. Campbell*. Mrc1 and DNA polymerase ε function together in linking DNA replication and the S phase checkpoint. Mol. Cell 2008, 32(1):106-117. (On the cover). [Previews] Labib Karim, Making Connections at DNA Replication Forks: Mrc1 Takes the Lead. Mol. Cell, 2008, 32(2):166-168. Huiqiang Lou, Zhenhong Duan, Tong Sun, and Li Huang*. Cleavage of double-stranded DNA by the intrinsic 3’-5’ exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol. Lett. 2004, 231: 111-117. Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, and Li Huang*. Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. J Biol. Chem. 2004, 279(1):127-32. Likui Zhang, Huiqiang Lou, et. al. Extremophile. Published online: 11 December 2009 |
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