段明星

教授

1970年，清华大学 学士

1984年，清华大学 硕士

现任清华大学教授，清华大学（生物科学与技术系）－隆力奇生物科技研究所所长

主要科研领域与方向：多肽蛋白质药物及核酸疫苗的研究：

多肽蛋白质药物的性质及功能；

多肽蛋白质药物的口服及缓释；

核酸疫苗的构建及免疫机理和免疫途径。

Selected Publications:

F.F.Zhuang, R.Liang, C.T.Zou, H.Ma, C.X.Zheng, M.X.Duan*.“High efficient encapsulation of plasmid DNA in PLGA microparticles by organic phase self-emulsification”, J.Biochem.Biophys.Methods 52 (2002) 169-178.

Bin Deng, Zheng Liu, Guoan Luo*, Hong Ma, Mingxing Duan*.“Rapid quantitative determination and assessment of insulin in oil formulation by micellar electrokinetic capillary chromatography”, Journal of Pharmaceutical and Biomedical Analysis. 27 73 - 80 (2002).

Liang Rong，Zhuang FengFeng, Meng Zheng, Zheng Changxue, Duan Mingxing*.“A New Potent Route of DNA Vaccine Inoculation: DNA-Liposome Complexes on Bare Skin Induce Antigen-Special Antibody Responses”, Molecules 8, 120 126. (2003).

Hong-Wei Wang, Yong Chen, Hsiuchin Yang, Xianchuan Chen, Ming-Xing Duan, Phang C. Tai* and Sen-Fang Sui*.“Ring Like Pore Structures of SecA: Implication for Bacterial Protein-Conducting Channels”. Proc.Natl.Acad.Sci.U.S.A. Vol.100 No.7 P4221-4226 (2003).

Xi-Ming Qin，Ming-Xing Duan*, Bin Deng, Xi-Cheng Liu, Qiang-Zhe Zhang, Zheng Liu, and Hong-Xuan He.“Isolation and Identification of a New Thymic Peptide from Calf Thymus”, Biochemistry(Moscow) 2004, 69(8): 921-925.

HongXuan HE, BaoHua ZHAO, LiYan LIU，Kai ZHOU, XiMing QIN, QiangZhe ZHANG, Xi LI, ChangXue ZHENG, and MingXing DUAN*.“The Humoral and Cellular Immune Responses in Mice Induced by DNA Vaccine Expressing the Sporozoite Surface Protein of Cryptosporidium parvum”, DNA AND CELL BIOLOGY Vol.23, No.5, P335-339 (2004).

Zhang Qiang-Zhe, Qin Xi-Ming,Dong Hai-Li, Liang Rong, He Hong-Xuan,Li Xi, Jiang Bei-Yu, Liu Xiang-Jun, Duan Ming-Xing*.“Efficient Protection of H5N1 Influenza Virus DNA Vaccine Delivering by Electroporation in Mammalian and Avian System”, Progress in Biochemistry and Biophysics Vol.32 No.8 p726-733 (2005).