词条 | 正向遗传学 |
释义 | § 简介 正向遗传学(forward genetics) A classical genetic approach, where one starts with a mutation phenotype and works toward identifing the mutated gene. § 相关 研究突变表型以确定突变基因的传统遗传学方法。 One of the first tools available to molecular geneticists is the forward genetic screen. The aim of this technique is to identify mutations that produce a certain phenotype. A mutagen is very often used to accelerate this process. Once mutants have been isolated, the mutated gene can be molecularly identified. 正向遗传学筛查是分子遗传学家最初可使用的一种方法,该技术意在检定产生特定表型的变异。为了提高变异的速度,常使用诱变剂来实现。而一旦分离出变异体,就可以鉴定出对应的突变基因。 |
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