黄青阳 性 别： 男 职 称： 教授 2001.1-2003.6 Research Associate，美国Creighton University 医学中心 导师：邓红文教授和Recker教授(美国骨和矿物研究学会主席) 1999.9-2001.1 博士后, 以色列Haifa University 进化研究所 导师：美国科学院院士Eviatar Nevo教授和A.B.Korol教授

个人简历

研究兴趣(中国人群复杂疾病的基因组学研究 水稻遗传育种研究 生物数学与统计遗传学的理论和方法研究)

研究项目

论文代表作

个人简历

1996.8-1999.7 博士，遗传学，武汉大学 导师：朱英国教授

1985.8-1988.7 硕士，植物遗传育种，四川农业大学 导师：荣廷昭院士和高之仁教授

教学

遗传学，分子遗传学，基因组学，生物统计学

研究兴趣

中国人群复杂疾病的基因组学研究

利用基因组学、基因芯片和蛋白质组学技术开展中国人群重大疾病(糖尿病、高血压、癌症、肥胖等)相关基因的鉴定研究；环境基因组学和药物基因组学研究。

水稻遗传育种研究

定位、克隆重要的农艺性状基因；水稻细胞质雄性不育与育 性恢复的分子机理研究；杂种优势的遗传基础研究；杂交水稻育种研究

生物数学与统计遗传学的理论和方法研究

生物数学与统计遗传学的理论和方法研究

研究项目

1. 中国人群2型糖尿病与几个候选基因的连锁与关联分析,国家自然科学基金

2. 中国人群2型糖尿病样本的收集与相关基因的研究,教育部留学回国人员科研启动基金

3. 中国人群复杂疾病的遗传学研究,华中师范大学引进杰出人才基金

论文代表作

1. Huang QY, Xu FH, Shen H, Deng H, Conway T, Liu YJ, Liu YZ, Li JL, Davies KM, Recker RR， Deng HW(2004). Genome wide screen for genes underlying bone sizes in ten refined skeletal sites: genetic heterogeneity and the significance of the refinement of traits, Physiol Genomics 17（3）：326-331

2．Huang QY, Xu FH, Shen H, Liu YJ, Liu YZ， Zhao LZ， Deng H, Conway T, Li JL, Davies KM, Recker RR， Deng HW(2004). The second stage genome scan for QTLs underlying BMD variation. Calcif Tissue Int, in press

3. Huang QY，Recker RR，Deng HW (2003) Searching for the osteoporosis gene(s) in the post-genome era: progress and challenge. Osteoporos Int 14(9):701-715

4．Huang QY，Shen H, Deng H, Conway T, Davies KM, Li JL, Recker RR， Deng HW (2003) Linkage and association of the CA repeat polymorphism of the IL-6 gene, obesity-related phenotypes, and bone mineral density in two independent Caucasians populations. J Hum Genet 48(8):430-437

5. Huang QY, Xu FH, Shen H, Deng HY, Liu YJ, Liu YZ, Li JL, Recker RR, Deng HW (2002). Mutation patterns at dinucleotide microsatellite loci in humans. Am J Hum Genet 70(3): 625-34

6. Huang QY, Beharav A, Li YC, Kirzhner V, Nevo E (2002). Mosaic microecological differential stress causes adaptive microsatellite divergence in wild barley, Hordeum spontaneum, at Neve Yaar, Israel. Genome 45(6): 1216-1229

7. 黄青阳，何予卿，景润春，朱仁山，朱英国，1999，利用微卫星标记定位水稻红莲型细胞质雄性不育恢复基因。科学通报，44（14）：1517-1520

8. Xu FH, Liu YJ, Deng H, Huang QY, Zhao LJ, Shen H, Liu YZ, Dvornyk V, Conway T, Li JL, Davies KM, Recker RR, Deng HW（2004）A follow-up linkage study for bone size variation in an extended sample. Bone 35(3):777-84

9. Liu YJ, Xu FH, Shen H, Liu YZ, Deng HY, Zhao LJ, Huang QY, Dvornyk V, Conway T, Davies KM, Li JL, Recker RR, Deng HW. (2004) A Follow-Up Linkage Study for Quantitative Trait Loci Contributing to Obesity-Related Phenotypes. J Clin Endocrinol Metab 89(2):875-882

10. Deng HW, Shen H, Xu FH, Deng H, Conway T, Liu YJ, Liu YZ, Li JL, Huang QY, Davies KM, Recker RR (2003) Several genomic regions potentially containing QTLs for bone size variation were identified in a whole-genome linkage scan. Am J Med Genet 119(2): 121-31

11. Liu YZ, Xu FH, Shen H, Deng H, Liu YJ, Zhao LJ, Dvornyk V, Conway T, Li JL, Huang QY, Davies KM, Recker RR, Deng HW (2003) Confirmation linkage study in support of the X chromosome harbouring a QTL underlying human height variation. J Med Genet 40(11):825-31

12. Deng HW, Xu FH, Huang QY, Shen H, Deng H, Conway T, Liu YJ, Liu YZ, Li JL, Zhang HT, Davies KM, Recker RR (2002) A whole-genome linkage scan suggests several genomic regions potentially containing quantitative trait Loci for osteoporosis. J Clin Endocrinol Metab 87(11): 5151-9

13. Deng HW, Xu FH, Liu YZ, Shen H, Deng H, Huang QY, Liu YJ, Conway T, Li JL, Davies KM, Recker RR (2002). A whole-genome linkage scan suggests several genomic regions potentially containing QTLs underlying the variation of stature. Am J Med Genet 113(1): 29-39

14. Deng HW, Deng H, Liu YJ, Liu YZ, Xu FH, Shen H, Conway T, Li JL, Huang QY, Davies KM, Recker RR (2002). A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet 70(5): 1138-51

15. Peng JH, Fahima T, Roder, Huang QY, Dahan A, Li YC, Grama A, Nevo E (2000). High-density molecular map of chromosome region harboring stripe-rust resistance genes YrH52 and Yr15 derived from wild emmer wheat, Triticum dicoccoides. Genetica 109(3): 199-210

国际会议摘要

1. Genetics of HL-type cytoplasmic male sterility and its fertility restoration in rice (Oryza Sativa L.). 18th International Congress of Genetics,1998, Beijing

2. QTL analysis of drought resistance in wild barley, Hordeum spontaneum,

I. Physiological trait, growth parameters and dry matter at the seedling stage under water stress. Plant & Animal Genome IX Conference, January 13-17, 2001.San Diego, USA

3. A large-scale whole-genome scan suggests several genomic regions containing QTLs for BMD variation. Second annual meeting of the great plains states society for molecular biology and genetics. May 21-22, 2001. Omaha, USA

4. Second stage of genome scan for QTLs influencing BMD variation.24th Annual Meeting of American Society of Bone and Mineral Research, September 20-24, 2002, San Antonio, Texas, USA

5. Dinucleotide repeat (CA) polymorphism of TNFR2, BMD, and BMI: linkage and association studies. Third annual meeting of the great plains states society for molecular biology and genetics. June 3-4, 2002, Omaha, USA

6. Genome scan for QTLs underlying bone size variation at ten refined skeletal sites: genetic heterogeneity and the value of the subdivision of traits. 52th Annual Meeting of American Society of Human Genetics, October 15-19, 2002, Baltimore, Maryland, USA