简历：

研究方向：

专家类别：

代表论著：

简历：

1965年8月生，研究员，主要研究方向为发育生物学。1999年于新加坡国立大学生物系获哲学博士学位；1999年-2003年在美国Case Western Reserve University医学院药学系做博士后研究；2003年-2005年在美国University of Pennsylvania医学院医学系分子心脏病学研究中心做博士后研究。2005年受聘为中科院水生生物研究所研究员。入选中国科学院“百人计划”。2006年获"百人计划"择优资助。

研究方向：

鱼类分子病理学

专家类别：

百人;杰青

代表论著：

1. Li, X., He, JY., Hu, W., Yin, Z. 2009. The essential role of endogenous ghrelin in growth hormone expression during zebrafish adenohypophysis development. Endocrinology (in press).（通讯作者）

2. Ma, L., Li, D., Wang, J., He, J., Yin, Z. 2009. Effects of Adrenergic Agonists on the Extrahepatic Expression of Vitellogenin Ao1 in Heart and Brain of the Chinese Rare Minnow (Gobiocypris rarus)。 Aquatic Toxicol. 91 (1): 19-25.

3. Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA. (2007). HDAC2 regulates the cardiac fetal gene program and hypertrophic responsiveness by modulating GSK3ß. Nature Medcine. 13(3): 324-331. (equal first author).

4. Kook, H., Yung, WW., Simpson RJ., Kee HJ., Shin S., Lowry JA., Loughlin., Yin Z., Epstein JA., Mackay JP. (2006). Analysis of the structure and function of the transcriptional coregulator HOP. Biochemistry 45(35):10584-10590.

5. Yin, Z., Gonzales, L., Kolla, V., Rath, N., Zhang, Y., Lu, MM., Kimura, S., Ballard, PL., Beers, MF., Epstein, JA. & Morrisey, EE. (2006). Hop functions downstream of Nkx2.1 and Gata6 to mediate HDAC-dependent negative regulation of pulmonary gene expression. Am. J. Physiol. Lung Cell Mol. Physiol. 291：L191-199.

6. Kee, HJ., Sohn, IS., Nam KI., Park, JE., Qian, YR., Yin, Z., Ahn, Y., Jeong MH., Bang, YJ., Kim, NK., Kim, JK, Kim, KK., Epstein JA & Kook, H. (2006). Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding. Circulation. 113(1):51-9.

7. Yin, Z., Jeni Haynie, Bryan R. Williams and Yu-Chung Yang. (2003). C114 is a novel IL-11-inducible nuclear dsRNA-binding protein that inhibits Protein Kinase R. J. Biol. Chem. 278, 22838-22845.

8. Yin, Z. Haynie, J., Yang, X.,. Han, B., Kiatchoosakun, S., Restivo, J., Yuan, S., Prabhakar, N. R., Herrup, K., Conlon, R. A., Hoit, B. D., Watanabe, M and Yu-Chung Yang. (2002) The essential role of Cited2, a negative regulator for HIF-1 in heart development and neurulation. Proc. Nat. Acad. Sci. USA. 99, 10488-10493.

9. Yin, Z. & Kwang, J. 2000. Molecular cloning of a carp Jak3 from activated leukocytes. Veterinary Immunology and Immunopathology. 74: 225-236.

10. Yin, Z., & Kwang, J. (2000) Carp interleukin-1b in the role of an immuno-adjuvant. Fish & Shellfish Immunology. 10: 375-378.

11. Yin, Z., & Kwang, J. (2000). Molecular isolation and characterisation of carp transforming growth factor b1 from activated leucocytes. Fish & Shellfish Immunology. 10: 309-318.