词条 | 涂晓明 |
释义 | 涂晓明,男,博士,副教授。 1976年出生于福建省。1993年至2002年就读于中国科技大学生命科学学院并先后获学士,硕士和博士学位。2002年8月至2005年7月在美国加州大学旧金山分校作博士后研究。2005年7月作为中国科技大学优秀人才引进,现为生命科学学院副教授。共发表论文十余篇。其中,近3年来以第一作者在Molecular Biology of the Cell、Journal of Cell Science、Journal of Biological Chemistry等杂志发表研究论文6篇(总影响因子超过30)。2006年入选国家教育部“新世纪优秀人才支持计划”。2005年11月起任安徽省细胞生物学会常务副秘书长。 主要研究兴趣: 1、 锥体虫细胞周期调控的分子机制的研究; 2、 锥体虫SUMO系统的研究; 3、 Kinesin家族蛋白成员在锥体虫中的功能研究; 4、 锥体虫作为模式生物用以进行高等真核细胞中核仁的研究。 承担的主要科研项目: 1:入选国家教育部“2005年新世纪优秀人才支持计划”; 2:主持承担国家自然科学基金项目“锥体虫动点相关蛋白Mad2,Skp1,TOG和中心体相关蛋白Spc97,Spc98在有丝分裂中的功能研究”; 3:主持承担中国科学院知识创新工程重要方向项目子课题“锥体虫作为生物模式用以进行高等真核细胞中核仁的研究”。 近期论文: Xiaoming Tu, Praveen Kumar, Ziyin Li and Ching C. Wang (2006) An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei. J. Biol Chem. 281:9677-9687. Ziyin Li*, Xiaoming Tu*, and Ching C. Wang (2006). Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei. Exp. Cell Res. 312:3504-3516. (*contributed equally) Xiaoming Tu, Joel Mancuso, W. Zacheus Cande and Ching C. Wang (2005) Distinct Cytoskeletal Modulations and Mechanisms Regulating G1/S Transition between Two Life Stages of Trypanosoma brucei Cytoskeletal. Journal of Cell Science. 118:4353-4364. Xiaoming Tu and Ching C. Wang (2005) Pairwise Knockdowns of cdc2-related Kinases (CRK) in Trypanosoma brucei Identified the CRKs for G1/S and G2/M Transitions and Demonstrated Distinctive Cytokinetic Regulations between Two Developmental Stages of the Organism. Eukaryotic Cell. 4:755-764. Xiaoming Tu and Ching C. Wang (2005) Coupling of Posterior Cytoskeletal Morphogenesis to the G1/S Transition in the Trypanosoma brucei Cell Cycle. Mol. Biol. Cell. 16:97-105. Xiaoming Tu and Ching C. Wang (2004) The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J. Biol. Chem. 279:20519-20528. Xiaoming Tu, Jihui Wu, Yingqi Xu and Yunyu Shi (2001) Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain. J. Biomol. NMR. 21:187-188. Xiaoming Tu, Yazhong Xiao, Wangyong Zeng and Yunyu Shi (2000) Expression and purification of a recombinant DNA-binding domain of ADR6 protein from Escherichia coli and its secondary structure characterization. Biochim. Biophys. Acta. 1481:167-174. He Zhang, Yuzhi Hong, Yazhong Xiao, Jing Yuan, Xiaoming Tu and Xiaoqing Zhang (2006) Efficient production of laccases by Trametes sp. AH28-2 in cocultivation with a Trichoderma strain. Applied Microbiology and Biotechnology. 73:89-94. Yazhong Xiao, Xiaoming Tu, J. Wang, M. Zhang, Quan Cheng, Wangyong Zeng, Yunyu Shi (2003) Purification, molecular characterization and reactivity with aromatic compounds of a laccase from basidiomycete Trametes sp. strain AH28-2. Appl. Microbiol. Biotechnol. 60:700-707. Wangyong Zeng, Xuecheng Zhang, Xiaoming Tu, Shouhong Guang, Yazhong Xiao and Yunyu Shi (2001) Expression and Purification of the DNA-Binding Domain of the Human Transcription Factor E2F1. Protein Expr. and Purif. 21:99-104. |
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