词条 | 胡良海 |
释义 | 2003.7 月于吉林大学化学学院获理学学士学位,同年被推荐免试到中科院大连化物所国家色谱中心硕博连读,2009.1 获理学博士学位,博士期间获中科院院长奖学金优秀奖、卢嘉锡优秀研究生奖、Eli Lilly 亚洲优秀博士论文奖等多项奖励。博士毕业后赴美国普渡大学生物化学系与癌症中心从事博士后研究,现通过吉林大学“优秀人才引进计划”以学术骨干身份加入吉林大学生命科学学院药物代谢研究中心。目前为止,已在Angew. Chem. Int. Ed., Anal. Chem., J. Proteome Res., J. Chromatogr.A 等较高水平国际杂志上发表论文20 余篇,他人引用400 余次,应邀在Anal. Chem,Expert Rev. Proteomics 和《药学学报》英文版上撰写综述多篇,参与撰写英文著作两章,申请国家发明专利一项,多次在国际国内学术会议上做口头报告。现为美国质谱学会(ASMS)会员,Anal. Chim. Acta, J. Sep. Sci., J. Pept. Sci.,《高等学校化学学报》和《色谱》等杂志审稿人。 代表性论文: 1. Lianghai Hu, John Paul Fawcett, Jingkai Gu. Protein target discovery of drug and its reactive intermediate metabolite by using proteomic strategy. Acta Pharm. Sinica B (“药物代谢与转运”专刊邀请综述) 2. Lianghai Hu, Anton Iliuk, Jacob Galan, Michael Hans, W. Andy Tao. Identification of drug targets in vitro and in living cells by soluble nanopolymer-based proteomics. Angew. Chem. Int. Ed. 2011, 50, 4133-4136. (被主编选为热点文章“Hot Paper”) 3. Anton Iliuk, Lianghai Hu, W. Andy Tao. Aptamer in bioanalytical applications. Anal. Chem. 2011, 83, 4440-4452. 4. Lianghai Hu, Houjiang Zhou, Yinghua Li, Shutao Sun, Lihai Guo, Mingliang Ye, Xiaofeng Tian, Jianren Gu, Shengli Yang, Hanfa Zou. Profiling of endogenous serum phosphorylated peptides by titanium (Ⅳ) immobilized mesoporous silica particles enrichment and MALDI-TOF MS detection. Anal. Chem., 2009, 81, 94–104.(被选为《分析化学》杂志2009 年第三期NEWS 栏目介绍) 5. Lianghai Hu, Mingliang Ye, Hanfa Zou, Recent advances in mass spectrometry-based peptidome analysis. Expert Rev. Proteomics, 2009, 6(4), 433-447. 6. Lianghai Hu, Karl-Siegfried Boos, Mingliang Ye, Ren’an Wu, Hanfa Zou, Selective on-line serum peptide extraction and multidimensional separation by coupling a restricted access material-based capillary trap column with nanoLC-MS/MS. J. Chromatogr. A, 2009, 1216, 5377-5384. 7. Lianghai Hu, Xin Li, Xinning Jiang, Houjiang Zhou, Xiaogang Jiang, Liang Kong, Mingliang Ye, Hanfa Zou, Comprehensive peptidome analysis of mouse livers by size exclusion chromatography prefractionation and nanoLC-MS/MS identification. J. Proteome Res., 2007, 6, 801-808. 8. Lianghai Hu, Xueguo Chen, Liang Kong, Xingye Su, Mingliang Ye, Hanfa Zou, Improved performance of comprehensive two-dimensional HPLC separation of traditional Chinese medicines by using a silica monolithic column and normalization of peak heights. J. Chromatogr. A, 2005, 1092, 191-198. |
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